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My father aged 68, some 8 months back was diagnosed for Spine TB and he started on AKT4 for 2 months, AKT3 for the next month but had to stop due to vision loss and following 5 months was taking Rifampicin and Isoniazid. His vision is almost back with some eye power complaint but he is complaining about arm pain midway from shoulder joint and elbow. I read that Isoniazid can cause these side effects. Also recent blood report shows hemoglobin at 10.9. I read this could be due to Rifampicin. What could be the reason and if it needs any urgent attention to treatment? FYI. He is taking 40 mg of pyridoxine, his blood work shows platelet count=130, ESR 94, CRP has come down from 67 to 8.4, LFT results are normal, His back pain is almost gone. Other symptoms at this moment are slight numbness around feet, constipation and dizziness upon movement. Remarks of Hemogram: RBCs: Mild anisopoikilocytosis. Predominantly macrocytic normochromic with macroovalocytes. WBCs: Mild Leukopenia is present. Platelets: Appear mildly reduced in smear. Macroplatelets are seen. Sugar levels are normal 93/142 Blood pressure is bit low 75/115.
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Arm pain is nothing to do with TB drugs. Haematological abnormality can be due to rifampicin, but not alrming to stop drug rifampicin.
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