Difficulty in breathing mainly in evening since 2 years for SOS I use foracort .now from 4 months my bilirubin level all (total ,direct, and indirect) is increased but SGPT and SGOT is normal and from 2 months I have constipation problem my regular cycle changed and sometimes stomach pain for 1 to 2 min and I am also have problem of allergy for that I took l dio 1 m SOS and I am also having sleep problem I can't sleep till late nights or sometimes whole night .now my IgE level is 802 ng/ml.