HI, My research with addiction like marijuana comes with a final conclusion that I want to share with all you Dr. I found that there is absolutely raise in consciousness and after effect fatigue, it's like after puff a joint 1 hour high then almost 2 hour fatigue, but it's much more good in comparison with alcohol ,where ratio is 2 - 3 hour very high then 7 - 8 hr fatigue, marijuana is able to do this, people can use it whenever they have requirements of high consciousness for almost 1 hour, but after it, there is must 2 hr fatigue. So its not possible for human to get all time artificial high consciousness with the help of drugs. A human with marijuana can be able to make himself high for 6 times and 6 hrs in one day. actually, after all our struggles we are able in keeping 50 present conscious in comparison with drugs. Consciousness mean how fast your nerve synapse is working, in this scenario environment pollution lifestyle posture also slow down our synapse speed. What you think?