Hi, I am 3 & half months pregnant. I came to know about it only 2 days back. Ultrasound looks normal. However. Backdating pregnancy I was on isotroin for the first ten days of conception. Doctors have told me the risks. I do not want to abort my baby but risks are huge. What should I do please guide. What are tha chances of a healthy baby in my case?
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Exposure to isotretinoin causes skin and limb defects in fetus when exposed during early pregnancy as it is the time when organs are formed. So it is a huge risk.
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Hello.. Its a very tricky situation.. The fact is that we don’t have exact data regarding what percentage of babies will be affected and what will be the degree of anomalies.. However first trimester exposure of isotretinoin may be associated with anomalies risk in upto 30% of cases .. By inhibiting neural crest cell migration during embryogenesis they result in cranial neural crest defect termed retinoic acid embryopathy..
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Kindly correlate with anomalies scan to know if its affected the baby.
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