My wife 57 years suffering from major depressive disorder for the last 17 months. Taking medicines but no improvement. Recently her blood count drastically reduced. haematologist gave 3 pints blood and her bone marrow test shows drug induced. So they stopped mirtaz, qutipin, trofisopam. They gave prothiaden 25 mg and advised to take 75 mg after 5 days. But it was told this medicine is not good for heart. Pl advise me.
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Every medicine has some side effect, since the treatment is done under the supervison of doctor they will timely monitor the results. At this age she need lot of attention, when you give time, value and attention which surely you may be giving but make sure whole surrounding envirnment is very positive. In hydrabad there are good unani doctors parallely you can also consult them considering current situation. The effect of thoughts on our physical health is well established. Each thought has an effect on the cells of the body. Never loose hope im sure she will get well soon.
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Dear lybrate-user, taking medicines for the long term and no improvement needs a review of diagnosis. Now that we know her counts reduced. We need to know why it is reduced. If it is drug-induced, it will recover after stopping the drug. Bone marrow test will not show that it is drug-induced. But the report will show the type of count reduction, like neutropenia. Except for clozapine, other psychiatric drugs (mirtaz, qutipin and tofisopam) rarely cause low blood count. In clozapine, the psychiatrist generally does blood count as a routine to prevent it happening. I would like the review of diagnosis, if confirmed, there are many antidepressants available apart from prothiaden.
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