Urgent. Pls pls pls advice. My father had trauma. He got hospitalized and recover fully buy he is having excessive thirst from that day. It's is I guess central diabetes mellitus after head trauma. He is taking minirin and silodal but having excessive thirst. Please advice. He had. History of pituitary macroadonema tumour and taking hormonal treatment from last 10 years.

Dr. Satyam ChakrabortyEndocrinologist14yrs exp

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Lt is central diabetes insipidus. Madam, your father should be given fluids as much as possible. The minirin dose needs to be titrated gradually with highest dose at night. Keeping track of the s.sodium levels at least once a week if not on alternate days is absolutely essential & the levels should be preferably maintained between 135- 150 meq/l.the patient needs an endocrinologist consultation.  

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Dr. Milind PatilEndocrinologist12yrs exp

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Do serum sodium osmolality and urine osmolality. The diabetes after pituitary macroadenoma requires monitoring of these test and dose adjustment of minrin tablet. Please consult your endocrinologist with these reports asap.  

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Dr. Sudipta Dutta DiabetologistDiabetologistyrs exp

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First of all, there is nothing like central diabetes mellitus. Sometimes, excess gh or acth release from pituitary from the tumor may cause hyperglycemia called as secondary diabetes. Low secretion of adh may cause excessive urination known as diabetes insipidus lead to excessive thirst. But sugar remains normal in the blood. So please be more specific about his illness and give a proper history of what hormones he is taking regularly.  

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