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Pleural effusion my friend has a adeno lung cancer stage 4 she has completed 6 round of carbo/pem on 26/11/20 her ct scan was on 10/12/20 an she was considered stable an the doctor will stop chemo and to re do the ct in feb he was totally happy with her results. Suddenly one 23/dec she star to cough a lot and to have a shoulder and shoulder blade pain and short breath while working she went to the er and they find pleural effusion and now they have drained 2000 ml so far I wonder how this can happen sudden and did not show in her ct scan in 10 dec how can cancer spread so fast in 2 weeks.
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Yes. This may happen in some cases. Typically after 6 cycles of double agent chemotherapy we keep patient on maintainance therapy with pemetrexed till disease progression. Else pt will need to be put on 2 nd line chemotherapy or immunotherapy. Other options include oral targeted therapy if she is positive for either of mutations like egfr, alk, ros 1, met, braf which can be checked on biopsy tissue.
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