Can efavirenz-600 mg + emtricitabine-200 mg + tenofovir disoproxil-300 mg be used as post exposure prophylaxis (pep) for hiv infection.

Question

Good evening lybrate-user. The drugs you have mentioned that are used as pep or post exposure prophylaxis are currently outdated. As the drug efavirenz 600 you have mentioned has been the essential first line drug in hiv infected for past 20 years. Recently the naco (national aids control organisation) has changed the first line medicine in view of probable resistance to all nrti drugs which includes efavirenz too, even in newly infected because of the possibility of mutations that might have occurred as it has been more than 20. Years since it's inception in the first line hiv medicine in india. So please consult a physician who have complete knowledge of hiv and art medicine. I have more than 10 years experience treating hiv disease. You can contact if you still need further assistance.

Chakravarthy S S · Accepted Answer

Good evening lybrate-user. The drugs you have mentioned that are used as pep or post exposure prophylaxis are currently outdated. As the drug efavirenz 600 you have mentioned has been the essential first line drug in hiv infected for past 20 years. Recently the naco (national aids control organisation) has changed the first line medicine in view of probable resistance to all nrti drugs which includes efavirenz too, even in newly infected because of the possibility of mutations that might have occurred as it has been more than 20. Years since it's inception in the first line hiv medicine in india. So please consult a physician who have complete knowledge of hiv and art medicine. I have more than 10 years experience treating hiv disease. You can contact if you still need further assistance.