I am a diabetic since 18 years aged 57 years. At present I am taking metride 2mg (glimpride 2mg metformin 500mg) before breakfast, Janumet before lunch (sitagliptin 50mg metformin 500mg) and metride 1mg ((glimpride 1mg metformin 500mg) before dinner. My question is whether same salt of other reputed manufacturer can be substituted with above medicines, because some times cost is about half of the medicine, If no, what can be the possible impact of changing the medicines without doctors advice.

Dr. Anirban BiswasEndocrinologist21yrs exp

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Yes, you can change the medicines with suitable substitutes if the cost difference is huge. But, simply put the cost is often decided by various factors including quality. After all you cannot compare a sony tv and micromax tv both same size but cost is half. The bottom line is, that you sugars should be in target. Just taking medicines for the sake of taking some treatment won't help you to prevent the complications of diabetes, a dreaded disease. So, try them out for a month or two, if the results are same, continue it, if not, then please get back to the original drugs. 

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