My wife's were lesser than normal (tested on 20/04/23. On 23/04/23, I had fever (max temp 102�f) with throatache. Took tab azithral 250 (twice a day for 5 days) wbc's increased to 3.61�10^3 (tested on 28.04.2023, doc suspected. Typhoid. My current symptoms are severe nausea (unrelieved with tab ibset, some headache, loss of appetite and raised body temp is between 99�f-100�f my typhoid igm is positive and typhoid igg is negative. Widal is negative. 0-1 pus cells is present in stool kindly tell me whether I have typhoid or not and what should be done for the same? If it's not typhoid, then why is my typhoid igm report positive? Kindly reply i'm confused.

Dr. Darshan KananiGeneral Physician2023yrs exp

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Without examination, I can not say whether it is typhoid or not. But typhoid seems less likely based on your history. Other causes of igm positivity: cross-reactivity with other bacteria: igm antibodies can sometimes cross-react with other bacterial infections, leading to a false positive result. Previous exposure or vaccination: if a person has been previously vaccinated against typhoid fever or has had a past infection, they may still have detectable igm antibodies in their blood. Non-typhoidal salmonella infection: other types of salmonella bacteria can cause infections that may lead to the production of igm antibodies. Other infections: certain viral infections, such as dengue fever, can also lead to the production of igm antibodies that may cross-react with typhoid fever tests. Lab error: false positive results can sometimes occur due to errors in the laboratory testing process.  

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