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The natural course of chronic hepatitis B progresses through three stages: immune tolerance, active disease, and a late phase with reduced viral replication Approximately 25 per cent of patients with chronic hepatitis B will develop cirrhosis, causing permanent and serious liver damage. Chronic carriers of HBV are far more likely to develop hepatocellularcarcinoma than non-carriers The course of hepatitis B is determined by many factors, including immune response, host genetic factors, and HBV mutations. Treatments include: Antiviral medications. Several antiviral medications ? including lamivudine (Epivir), adefovir (Hepsera), telbivudine (Tyzeka) and entecavir (Baraclude) ? can help fight the virus and slow its ability to damage your liver. . Interferon alfa-2b (Intron A). . Liver transplant.
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