Medicine For Chronic Myeloid Leukemia

If BCR ABL1 transcript is positive as you have stated, then it confirms a diagnosis of CML. In that case you have to take Imatinib or other TKIs for the treatment. It cannot be ET if BCR ABL is positive. 

1 person found this helpful

Dr. Lalit RautFellowship In Leukemia & Stem Cell Transplant, DM - Clinical Haematology, MD - MedicineHematologist

86% (30 ratings)

Ask Free Question

There are minor side effects of imatinib. Not everyone gets them. You need to discuss them with your hematologist. Don't stop the medicine until you doc tells you to. 

2 person found this helpful

Dr. Saul PereiraReparenting Technique, BA, BEdPsychologist

94% (49777 ratings)

Ask Free Question

You can use some of the suggestions listed below to help to quit smoking. However all success depends entirely on his motivation to want to give up. You can shae these suggestions with him too: You have to quit cold turkey because the body and mind will torture you endlessly while attempting a reduction in smoking. The tobacco tar in cigarette smoke lines your lung with huge patches that make that portion dysfunctional. Your oxygen carrying capacity is jeopardized, and breathing is impinged on. But don’t be discouraged because it is not too late even now to reverse all the ill-effects of smoking. I don’t know what other organs could be damaged but do go for a thorough medical check-up to assess the effects of your abuse. Regarding improving your lungs, do a lot of aerobic exercise breathing through your nostrils only. Then there are a lot of deep breathing exercises in Yoga which you can learn too. Deep breathing cleanses your system and lungs and restores it to good health. Deep breathing uses the 80% of the lungs which are not normally used in normal breathing and even when exerting yourself. The greatest effect is in the lungs because this substance is processed through the respiratory system directly through the lung surface. When quitting, you must take one day at a time; though you must give up all smoking at once, and promptly. If you look too far ahead you will get discouraged and will give up. If you sit and count the number of days you have given up, that will also focus too much on achievement. You must focus on the here and now, on that day to be precise. After all quitting is not that easy due to many factors. So even if you fail one day, you must try and try again. Very few people succeed in their first attempt. Your persistence will eventually pay off. The urge to discontinue is hampered by many factors but the worst of them is the conditioning. In fact, these conditions can exist all through the day, unlike other addictions. But your desire to want to stop is the most important factor. It is important to find out about the ill-effects of smoking to have a reason that alarms you about continuing the habit. The information is really scary but true and you must remind yourself about this every day. The nicotine in tobacco smoke stimulates the heartbeat to raise the blood pressure in no time at all. So you must avoid it like the plague: it is just very bad medicine for you. In fact, it is highly toxic too. You will need to stop smoking or consuming any tobacco related items with immediate effect. You should start vigorous exercises, gradually increasing it over a period of time. Do deep breathing exercises every time you feel like smoking (try Yoga), and replace the oral urge with some healthy food substitute to satiate the need. You may also take hard candy or chew gum. If the urge is too strong, then use nicotine gums and nicotine patches, for a little while until the smoking drive reduces, substantially. You may also join Smokers Anonymous in your city where the support is really extraordinary for like-minded people who are also in the same situation. Keep yourself occupied or engaged with interesting activities during the times when it is most tempting. Keep the company of non-smokers for some time i.e. At least for the first 21 days. Above all announce it to everyone that you have quit smoking. Here’s a piece of very good advice: even if you accidentally/willfully take a cigarette, it is not the end of the world – you can start the cessation all over again. You must persevere with the best support until you defeat this addiction. Counseling is very useful in the initial stages and when temptations are at their highest. You could also join twitter2quit program and enjoy its success to give up smoking. These are the possible effects of cigarette smoking: Summary: (Source: Center for Disease Control and Prevention) •Cigarette smoking causes more than 480,000 deaths each year in the United States. This is nearly one in five deaths. •More than 10 times as many U.S. Citizens have died prematurely from cigarette smoking than have died in all the wars fought by the United States during its history. •Smoking causes about 90% (or 9 out of 10) of all lung cancer deaths in men and women. 1,2 More women die from lung cancer each year than from breast cancer. •About 80% (or 8 out of 10) of all deaths from chronic obstructive pulmonary disease (COPD) are caused by smoking. •Cigarette smoking increases risk for death from all causes in men and women. •Smoking is estimated to increase the risk— oFor coronary heart disease by 2 to 4 times oFor stroke by 2 to 4 times oOf men developing lung cancer by 25 times •Of women developing lung cancer by 25.7 times •Smoking causes diminished overall health, increased absenteeism from work, and increased health care utilization and cost. •Smoking causes stroke and coronary heart disease. •Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease. •Smoking damages blood vessels and can make them thicken and grow narrower. This makes your heart beat faster and your blood pressure go up. Clots can also form. •Blockages caused by smoking can also reduce blood flow to your legs and skin. •Lung diseases caused by smoking include COPD, which includes emphysema and chronic bronchitis. •Cigarette smoking causes most cases of lung cancer. •If you have asthma, tobacco smoke can trigger an attack or make an attack worse. •Smokers are 12 to 13 times more likely to die from COPD than nonsmokers. Smoking can cause cancer almost anywhere in your body: •Bladder •Blood (acute myeloid leukemia) •Cervix •Colon and rectum (colorectal) •Esophagus •Kidney and ureter •Larynx •Liver •Oropharynx (includes parts of the throat, tongue, soft palate, and the tonsils) •Pancreas •Stomach •Trachea, bronchus, and lung •Smoking can make it harder for a woman to become pregnant and can affect her baby's health before and after birth. Smoking increases risks for: oPreterm (early) delivery oStillbirth (death of the baby before birth) oLow birth weight oSudden infant death syndrome (known as SIDS or crib death) oEctopic pregnancy oOrofacial clefts in infants •Smoking can also affect men's sperm, which can reduce fertility and also increase risks for birth defects and miscarriage. •Smoking can affect bone health. OWomen past childbearing years who smoke have weaker bones than women who never smoked, and are at greater risk for broken bones. •Smoking affects the health of your teeth and gums and can cause tooth loss. •Smoking can increase your risk for cataracts (clouding of the eye’s lens that makes it hard for you to see) and age-related macular degeneration (damage to a small spot near the center of the retina, the part of the eye needed for central vision). •Smoking is a cause of type 2 diabetes mellitus and can make it harder to control. The risk of developing diabetes is 30–40% higher for active smokers than nonsmokers. •Smoking causes general adverse effects on the body, including inflammation and decreased immune function. •Smoking is a cause of rheumatoid arthritis. 

5 person found this helpful

Dr. G.R. AgrawalDHMS (Hons.)Homeopath

95% (38414 ratings)

Ask Free Question

Hello, She is suffering from gastric disorder. She should tk, plenty of water to hydrate her body. She should follow the diatery regulation advised by her Dr. She should tk, homoeopathic medicine: Calcarea carb 30-5 drops, thrice. Acid sulph 30-5 drops. Thrice. Report wkly, please. Tk, care. 

3 person found this helpful

Dr. Princy KhandelwalBHMSHomeopathy Doctor

92% (17687 ratings)

Ask Free Question

Hello, Your complete symptom picture is required for the prescription of proper medicines.So share more symptoms. Homoeopathy is based on the totality of symptoms. thanks. 

0 person found this helpful

Dr. Pritam MohapatraPost Doctoral Research (Ph.D.) (A.M) (Oncology), PGCert.- Integrative Oncology For Physicians (MSKCC, N.Y, USA), Doctor of Natural Medicine (N.D/ N.M.D), PGDip.- Clinical Counseling, PGDip.- Oncology & Haematology (A.M), Cert.- Ayurveda (I), CME Cert. - Clinically Relevant Herb-Drug Interactions (Cine-Med Inc. USA), PGCert.- Homeopathic Oncology (CCHO), PGCert.- Advanced Homeopathic Oncology (PGCCHO), Cert.- Immunotherapy Guidelines (NSCLC), Cert.- Advances in Cancer Immunotherapy, Cert.- Cancer Nutrition, PGCert.- Advanced Strategic Management Programme (APSM), B.E CSEAlternative Medicine Specialist

92% (1378 ratings)

Ask Free Question

Hi, imatinib 400 mg, as I understand, is an approved targeted therapy for front-line management of chronic myeloid leukemia (cml), success of which depends on whether or not it has been able to achieve a timely haematological response as expected. Imatinib is good so long as your disease is chronic, not advanced and is not resistant to imatinib. Your medical oncologist can best comment on the overall survival aspects, nevertheless. However, its advisable that you complement conventional care with appropriate alternative medicines so as to fast track treatment, and optimize clinical outcomes. 

2 person found this helpful

Dr. SheebaNutritionist, Diploma In Cosmeto Dermatology , BHMSHomeopath

92% (165 ratings)

Ask Free Question

.first is the desire to quit smoking and second is medication.smoking affects the lungs.and chain smokers often suffer from lung or throat cancer.so the earlier the better you leaveit.. 

0 person found this helpful

Dr. Saul PereiraReparenting Technique, BA, BEd, Transactional AnalysisPsychologist

94% (49777 ratings)

Ask Free Question

Summary: (Source:Center for Disease Control and Prevention) • Cigarette smoking causes more than 480,000 deaths each year in the United States. This is nearly one in five deaths. • More than 10 times as many U.S. citizens have died prematurely from cigarette smoking than have died in all the wars fought by the United States during its history. • Smoking causes about 90% (or 9 out of 10) of all lung cancer deaths in men and women.1,2 More women die from lung cancer each year than from breast cancer. • About 80% (or 8 out of 10) of all deaths from chronic obstructive pulmonary disease (COPD) are caused by smoking. • Cigarette smoking increases risk for death from all causes in men and women. • Smoking is estimated to increase the risk— o For coronary heart disease by 2 to 4 times o For stroke by 2 to 4 times o Of men developing lung cancer by 25 times • Of women developing lung cancer by 25.7 times • Smoking causes diminished overall health, increased absenteeism from work, and increased health care utilization and cost. • Smoking causes stroke and coronary heart disease. • Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease. • Smoking damages blood vessels and can make them thicken and grow narrower. This makes your heart beat faster and your blood pressure go up. Clots can also form. • Blockages caused by smoking can also reduce blood flow to your legs and skin. • Lung diseases caused by smoking include COPD, which includes emphysema and chronic bronchitis. • Cigarette smoking causes most cases of lung cancer. • If you have asthma, tobacco smoke can trigger an attack or make an attack worse. • Smokers are 12 to 13 times more likely to die from COPD than nonsmokers. Smoking can cause cancer almost anywhere in your body: • Bladder • Blood (acute myeloid leukemia) • Cervix • Colon and rectum (colorectal) • Esophagus • Kidney and ureter • Larynx • Liver • Oropharynx (includes parts of the throat, tongue, soft palate, and the tonsils) • Pancreas • Stomach • Trachea, bronchus, and lung • Smoking can make it harder for a woman to become pregnant and can affect her baby's health before and after birth. Smoking increases risks for: o Preterm (early) delivery o Stillbirth (death of the baby before birth) o Low birth weight o Sudden infant death syndrome (known as SIDS or crib death) o Ectopic pregnancy o Orofacial clefts in infants • Smoking can also affect men's sperm, which can reduce fertility and also increase risks for birth defects and miscarriage. • Smoking can affect bone health. o Women past childbearing years who smoke have weaker bones than women who never smoked, and are at greater risk for broken bones. • Smoking affects the health of your teeth and gums and can cause tooth loss. • Smoking can increase your risk for cataracts (clouding of the eye’s lens that makes it hard for you to see) and age-related macular degeneration (damage to a small spot near the center of the retina, the part of the eye needed for central vision). • Smoking is a cause of type 2 diabetes mellitus and can make it harder to control. The risk of developing diabetes is 30–40% higher for active smokers than nonsmokers. • Smoking causes general adverse effects on the body, including inflammation and decreased immune function. • Smoking is a cause of rheumatoid arthritis. Measures to quit smoking: When quitting, you must take one day at a time; though you must give up all smoking at once, and promptly. If you look too far ahead you will get discouraged and will give up. If you sit and count the number of days you have given up, that will also focus too much on achievement. You must focus on the here and now, on that day to be precise. After all quitting is not that easy due to many factors. So even if you fail one day, you must try and try again. Very few people succeed in their first attempt. Your persistence will eventually pay off. The urge to discontinue is hampered by many factors but the worst of them is the conditioning. In fact these conditions can exist all through the day unlike other addictions. But your desire to want to stop is the most important factor. It is important to find out about the ill-effects of smoking to have a reason that alarms you about continuing in the habit. The information is really scary but true and you must remind yourself about this every day. The nicotine in tobacco smoke stimulates the heart beat to raise the blood pressure in no time at all. So you must avoid it like the plague: it is just very bad medicine for you. In fact it is highly toxic too. You will need to stop smoking or consuming any tobacco related items with immediate effect. You should start vigorous exercises, gradually increasing it over a period of time. Do deep breathing exercises every time you feel like smoking (try Yoga), and replace the oral urge with some healthy food substitute to satiate the need. You may also take hard candy or chewing gum. If the urge is too strong, then use nicotine gums and nicotine patches, for a little while until the smoking drive reduces, substantially. You may also join Smokers Anonymous in your city where the support is really extraordinary for like-minded people who are also in the same situation. Keep yourself occupied or engaged with interesting activities during the times when it is most tempting. Keep the company of non-smokers for some time i.e. at least for the first 21 days. Above all announce it to everyone that you have quit smoking. Here’s a piece of very good advice: even if you accidentally/willfully take a cigarette, it is not the end of the world – you can start the cessation all over again. You must persevere with the best support until you defeat this addiction. Counseling is very useful in the initial stages and when temptations are at their highest. 

9 person found this helpful

Dr. Raghu Vamsi NadimintyM.CH - Surgical Oncology, MBBSOncologist

91% (34 ratings)

Ask Free Question

Dear there is a medicine for a type of blood cancer known as chronic myeloid leukemia (cml). The name of the drug is imatinib mesylate (not imatenef as seen in those messages). It has improved the chance of survival for this group of patients by a big margin compared to previous treatments. Regards 

1 person found this helpful