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Colostrum (Human Anatomy): Image, Functions, Diseases and Treatments

Last Updated: Dec 05, 2022

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After giving birth, the mammary glands release colostrum, which is the first form of breastmilk. It is abundant in vitamins, antibodies, and antioxidants that support the growth of a newborn's immune system. Within two to four days of your baby's birth, it transforms into breast milk. Colostrum is more yellow in colour and thicker than regular breast milk.

Does leaking colostrum mean labor is close?

It's not a sign that you're about to give birth if colostrum is coming out of your nipples. Colostrum leakage is normal, and some people have noticed it in the second trimester. While some people have solidified colostrum on their nipples, others show no signs of colostrum leakage. If you are leaking colostrum, you could use breast pads that you can throw away or wash.

Can you express colostrum if you're pregnant?

It is possible to start producing colostrum around the 37th week of pregnancy, and some individuals find that it is helpful. Hand expressing refers to the process of extracting breast milk by applying rhythmic pressure to the breasts. However, there are potential dangers associated with expressing colostrum before the birth of the baby, such as contractions and early labour. When specific health factors are present, it may help people who are at risk for preterm delivery, a poor milk supply, or both.

Before pumping your colostrum, discuss the procedure with your doctor. If you are producing colostrum, it could be okay to collect and preserve it until the time your baby is born.

What is colostrum made of?

Low in fat and sugar, colostrum has a high protein content. It is stuffed with of white blood cells, which make antibodies. The newborn's immune system will be strengthened by these antibodies, defending him or her against illness. Because colostrum is so concentrated and nutrient-dense, it doesn't take much for your baby's stomach to benefit from it, even in small doses.

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What kind of nutrients are in colostrum?

A special combination of nutrients found in colostrum protect and nourish your baby. It consists of items such as: Immunoglobulin A (IgA) (an antibody), Lactoferrin (a protein which helps prevent infection), Leukocytes (white blood cells) (white blood cells), and EGF (epidermal growth factor) (a protein that inspires cell growth).

Carotenoids (antioxidants) and vitamin A give it its colour. Vitamin A is essential for your baby's eyesight, skin, and immune system. Colostrum contains significant amounts of magnesium, which supports the heart and bones of your infant, as well as copper and zinc, which support immunity.

What's the difference between colostrum and breast milk?

During pregnancy, the breasts produce colostrum, a nutrient-rich first milk. Several days after birth, it transforms into transitional breast milk. However, modest quantities of colostrum continue to be present in breast milk for many weeks. There are two major distinctions between colostrum and breast milk: Immunoglobulins included in colostrum strengthen the infant's immune system and provide protection against disease. Colostrum has double the amount of protein. Zinc is four times more abundant in it. Colostrum is simpler to digest since it contains less fat and sugar. It is more yellow and viscous.

What are the stages of breast milk?

The three stages of breast milk are mature milk, transitional milk, and colostrum. The first milk you make after giving birth is called colostrum, and it lasts for two to four days. Beginning four days after birth, transitional milk lasts for around two weeks. Mature milk is the amount of milk you produce for about 14 days after giving birth or until you run out.

When does colostrum turn to milk?

Colostrum will change into transitional milk in three to four days. This is sometimes referred to as 'milk coming in.' You will notice that your breasts are firm, sensitive, and full. It indicates that your milk production has increased. Your child's stomach has enlarged at this point, allowing them to swallow more milk at each meal. Transitional milk becomes mature milk once your milk production is developed and your system has stabilised.

What makes colostrum turn to breast milk?

Colostrum production is aided by the placenta's production of pregnancy hormones.Once the placenta separates out from uterus, the hormone progesterone reduces considerably (after your baby is born). This decrease in progesterone causes your breasts to produce milk.

What does colostrum look like?

Colostrum is frequently a rich, deep yellow or orange hue, resembling the yolk of an egg. This is due to the high quantities of beta carotene it contains. It can occasionally seem white, transparent, or creamy. The consistency differs from person to person, but it is thicker than breast milk (or cow's milk). Colostrum is frequently viscous and may contain trace amounts, which is normal..

How do I know I am making colostrum?

Around 12 and 18 weeks of pregnancy, your body starts making colostrum. A tablespoon to an ounce of colostrum is typically produced in the first 24 hours following delivery by most mothers. This slowly gets bigger until the third or fourth day, when the milk starts to change. Most of the time, you won't know if you're making colostrum, but it's very rare that you won't be able to. If your baby is receiving colostrum, they will stay the same weight and wet their diapers.

How long do you have colostrum?

Up to around five days since the baby is born, your body will keep making colostrum. Around this time, it changes into transitional milk. After about 14 days, it changes again into mature milk. Your breast milk has traces of colostrum for 6 weeks.

Colostrum Functions

Your mammary glands, which are located in your breasts, are responsible for producing milk. Colostrum is more than just the 1st milk your baby drinks after birth.It is extremely rich in nutrients and antibodies that can fight infections and safeguard your baby. It offers a potent, special immunity that it alone can offer. Because your baby only requires a slight amount of colostrum, it also aids in their development of their ability to suck, swallow, and breathe while feeding.

What are the benefits of colostrum?

Colostrum provides concentrated nutrition while bolstering your baby's immune system. It supports the immune system growth of your child. A healthy gut can be established by coating the intestines. This helps to prevent the absorption of potentially harmful bacteria. It provides the best nourishment for a newborn. It has a laxative effect, which aids in the removal of meconium (your baby's 1st poop) and reduces the risk of jaundice. It helps keep full-term babies' blood sugar levels from falling too low.

Why is colostrum good for newborns?

Colostrum contains all the essential nutrients during a newborn's first few days of life. It is also abundant in vitamins and minerals, which will strengthen the immune system of your child.The gradual release of colostrum through your nips allows your infant to learn how to breastfeed (nurse). Learning to breastfeed involves practise and requires your infant to simultaneously learn to suck, swallow, and breathe.

Can you pump colostrum?

Due to its thick composition, colostrum may be difficult to extract from the breast using a breast pump. The majority of individuals advise and prefer to express colostrum via the use of their hands. Colostrum is often produced in greater quantities when it is expressed by hand rather than using a pump.

The first milk that your body generates after conception is called colostrum (pronounced kuh-loss-trum). It is produced in your mammary glands, sometimes known as your breasts, and plays a significant part in the development of your child's immune system. If you intend to breastfeed your child (either by nursing or chestfeeding), this will be the first milk that your child consumes that comes from your breasts.

Colostrum may be extracted by hand if you would not want to breastfeed or maybe if your infant is having trouble latching on to breast milk. It is rich in protein, immunoglobulins (antibodies), vitamins, and minerals, all of which contribute to the development of your baby's immune system. Because of its value, it is often referred to as 'liquid gold.'

Colostrum Conditions and Disorders

  • Galactorrhea: Galactorrhea is a milky nipple discharge unrelated to the normal milk production of breast-feeding. Galactorrhea itself isn't a disease, but it could be a sign of an underlying problem.
  • Lactation insufficiency: A poor milk supply while nursing can result from a number of circumstances, including delaying breastfeeding for an extended period of time, not breastfeeding frequently enough, supplementing breastfeeding, using inadequate latch techniques, and using certain drugs. Sometimes previous breast surgery affects milk production.
  • Prolactin (PRL) deficiency: It can be characterised as the loss of anterior pituitary cells that secrete PRL, leading to lower or absent PRL levels in the serum.
  • Hyperlactation: Early on during breastfeeding, it results in full, leaking breasts that don't noticeably soften after a feeding. Painful milk letdowns, severe engorgement, and breast pain are frequent..
  • Marasmus: It has a severe protein and calorie deficiency. Infants and young children are more likely to develop it. Dehydration, muscle and fat loss, and weight loss are typical outcomes. Usually, breastfeeding prevents marasmus.
  • Kwashiorkor: More protein than calories are severely deficient. Marasmus occurs more frequently than kwashiorkor. It happens when the second child is born and the second child takes the place of the first child at the mother's breast.

What happens if you don't produce colostrum?

It is uncommon for someone to produce no colostrum at all. If you feel as though your breasts aren't producing any milk, it's normal to worry that your child isn't getting enough. Your baby's tiny stomach will be satisfied with a small amount of colostrum.

Colostrum Tests

  • Physical exam: during which your doctor may try to express some of the fluid from your nipple by gently examining the area around your nipple. Your doctor may also check for breast lumps or other suspicious areas of thickened breast tissue.
  • Analysis of fluid discharged: Analysis from the nipple, to see if fat droplets are present in the fluid, which can help confirm the diagnosis of galactorrhea.
  • Blood test: to measure your body's prolactin levels. Your doctor will almost certainly also examine your thyroid-stimulating hormone (TSH) level if your prolactin level is excessive.
  • Pregnancy test: in order to rule out pregnancy as a potential reason for nipple discharge.
  • Mammography, ultrasound or both: To obtain images of your breast tissue if, during the course of your physical examination, your doctor finds a breast lump or other concerning breast or nipple changes.
  • Magnetic resonance imaging: If your blood test shows an elevated prolactin level, your doctor may recommend an MRI of your brain to look for a tumour or other abnormality of your pituitary gland.Culture and Sensitivity Aerobic test is performed on a sample of breast milk to evaluate the level of Culture of the pathogenic organisms in the breast milk. The test is performed to make sure for any Breast Infection once during the treatment and post treatment of Breast Infection.
  • Prolactin test: The PRL test quantifies the prolactin concentration in the body. A hormone produced by the pituitary is called prolactin. Throughout pregnancy and after delivery, prolactin induces the breasts to expand and produce milk. For expectant moms and new mothers, prolactin levels are typically high.
  • Biopsy: When the breasts continue to develop throughout pregnancy and feel solid and nodular, it is conceivable that a tumour mass may mistakenly be identified as normal tissue. So, the purpose of this test is to look for the existence of a tumour.Ultrasonography: Breast ultrasound during pregnancy reveals enlarged, hypoechogenic non-fatty fibroglandular tissue with widespread characteristics.

Colostrum Treatments

Supplementary feeding: Formula or (better yet) donor milk is required if the mother's milk supply is insufficient for the infant to receive enough nutrients. Instead of replacing nursing, supplements should be provided right away after a breastfeeding session.

Colostrum Medicines

  • Metoclopramide and Chlorpromazine: Due to its galactagogue effects, metoclopramide and chlorpromazine may aid some lactationally ineffective moms in returning to normal milk supply.
  • Galactagogues: Also known as lactogogues, are drugs or other substances thought to help in the beginning, continuing, or enhancing of mother milk production.
  • Metoclopramide: It encourages breastfeeding by preventing dopamine from being released into the central nervous system.
  • Domperidone: When given to healthy women, domperidone raises mean blood prolactin levels.
  • Antipsychotic sulpiride: The typical antipsychotic sulpiride acts as a galactogogue by raising hypothalamic prolactin releasing hormone.
  • Thyrotropin Releasing Hormone: It promotes the release of prolactin and TSH, which causes nursing women to produce more milk.

How do you store pumped colostrum?

IIf you and your doctor determine that expressing and storing colostrum is a good idea, there are certain guidelines to keep in mind. The first step is to use a clean syringe or container to keep the colostrum in. The shelf life in the fridge is roughly 2-3 days. After three days, you should transfer it to the freezer. Colostrum has a minimum shelf life of three months when stored in the freezer.

How much colostrum does a newborn need?

The stomach of your brand-new baby is around the size of a marble. They only require around one ounce of colostrum each day at this point. This amounts to around one teaspoon per serving (you can expect to feed the baby eight to 10 times in the first few days). Each day, the amount of colostrum (and subsequently, transitional milk) your baby needs steadily increases as their stomach gets bigger. Your body will eventually adjust to generating normal breast milk, at which point your supply of milk will rise to suit their requirements.

Do I need to supplement?

You really shouldn't feel the need to supplement. When it comes to feeding your newborn, even a small amount of colostrum may go a long way. Make sure to check in with your baby's healthcare practitioner to ensure that he or she is continuing to put on weight. If your child is wetting their diapers and appears to be content, it is unlikely that they require additional nutrition.

Is it okay to squeeze out colostrum?

After you reach full-term pregnancy, it is typically acceptable to squeeze out colostrum (37 weeks). If you want to do this before the birth of your child, talk to your doctor beforehand. To manually extract colostrum for your baby, take the necessary actions:

Keeping your hand in a 'C' form, cup your breasts. Your thumb should be placed above your nipple, and four fingers must be placed under your breast.Squeeze your nipple and areola lightly using your thumb and index finger.

Repeat again and in a regular sequence. While applying pressure, keep your fingers from sliding. Try shifting your fingers to a different location if the colostrum doesn't come out.

Within minutes, the colostrum should begin to slowly drain. It comes out in droplets and is thick. This can be done several times daily.Please keep in mind that extracting colostrum before the birth of your child contains dangers. Some people may experience premature labour or contractions. Before expressing colostrum, consult with your healthcare professional.

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Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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Reviewed ByDr. Bhupindera Jaswant SinghMD - Consultant PhysicianGeneral Physician

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