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Melanin Amino Acid: Types, Benefits and Side Effects

Last Updated: Jul 04, 2023

What is melanin?

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Melanin is a pigment that is responsible for the color of our skin, hair, and eyes. It is produced by cells called melanocytes, which are found in the skin and other parts of the body. There are several types of melanin, including eumelanin and pheomelanin, which determine the specific shades of color in an individual.

How Melanin Reacts to the Sun?

Melanin responds to the sun by producing more of itself in reaction to UV rays. This aids in shielding the skin from the sun's damaging effects, including sunburn and skin cancer. When the skin is exposed to UV radiation, the melanocytes increase the production of melanin, which absorbs and scatters the UV radiation, helping to prevent DNA damage. However, too much sun exposure can lead to an excess of melanin production, which can result in hyperpigmentation, or dark spots on the skin.

What is melanin’s function?

Melanin's main purpose is to shield the skin from the sun's damaging rays. It absorbs and scatters UV radiation, helping to prevent DNA damage and skin cancer. Melanin is also involved in the regulation of body temperature and the production of vitamin D. When UV radiation from the sun hits the skin, it stimulates the production of melanin as well as vitamin D. In addition, melanin helps to regulate body temperature by absorbing and releasing heat.

Where is melanin produced?

Melanin is produced in the melanocytes, which are found in the skin, hair follicles, and other parts of the body. When these cells are stimulated by UV radiation or other factors, they produce more melanin. The production of melanin is influenced by genetics and environmental factors, such as UV radiation.

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What are the types of melanin?

There are two main types of melanin that contribute to the color of our skin, hair, and eyes; eumelanin and pheomelanin.

  • Eumelanin: This pigment is responsible for the shades of brown, black, and gray. It is produced in higher amounts in people with darker skin, while those with lighter skin produce lower amounts. Eumelanin is also found in the iris of the eye and contributes to the color of the iris.
  • Pheomelanin: This pigment is responsible for the shades of red and yellow. It is produced in higher amounts in people with lighter skin, while those with darker skin produce lower amounts. Pheomelanin is also found in the hair and is responsible for determining the color of the hair.

How does melanin affect skin color?

Melanin affects skin color by determining the amount and type of pigment produced in the skin. The proportionate production rates of eumelanin and pheomelanin determine the distinct skin tones. For example, if an individual produces a higher amount of eumelanin and a lower amount of pheomelanin, their skin, hair, and eyes will be darker in color. On the other hand, if an individual produces a higher amount of pheomelanin and a lower amount of eumelanin, their skin, hair, and eyes will be lighter in color. The combination of these two pigments creates the wide range of colors that are seen in human skin, hair, and eyes.

How does melanin protect the skin?

Melanin is a pigment that plays a vital role in protecting the skin from the harmful effects of the sun. It does this by absorbing and scattering UV radiation, which can cause DNA damage and skin cancer. When the skin is exposed to UV radiation, the melanocytes, or cells that produce melanin, increase the production of melanin in response. This helps to absorb and scatter the UV radiation, reducing the risk of DNA damage.

In addition to its role in protecting the skin, melanin also helps to regulate body temperature. It does this by absorbing and releasing heat, which helps to maintain a stable body temperature. Melanin is also involved in the production of vitamin D, which is essential for the absorption of calcium and the maintenance of strong bones. Vitamin D is produced when UV radiation from the sun hits the skin and stimulates the production of melanin and vitamin D.

What are the benefits of melanin?

There are several benefits of melanin, more than protection from the sun, regulation of body temperature, and the production of vitamin D. Here some of the lesser knowns benefits of melanin;

  • Melanin helps to protect the skin from the harmful effects of the sun. It absorbs and scatters UV radiation, which can cause DNA damage and skin cancer
  • Melanin helps to regulate body temperature. It absorbs and releases heat, which helps to maintain a stable body temperature
  • Melanin is involved in the production of vitamin D, which is essential for the absorption of calcium and the maintenance of strong bones. Vitamin D is produced when UV radiation from the sun hits the skin and stimulates the production of melanin and vitamin D
  • Melanin helps to maintain the overall health of the skin. It contributes to the skin's natural moisturizing and repairing processes and helps to keep the skin smooth and supple
  • Melanin helps to protect the hair and scalp from the damaging effects of the sun. It absorbs and scatters UV radiation, which can cause dryness, breakage, and hair loss
  • Melanin helps to protect the eyes from the harmful effects of the sun. It absorbs and scatters UV radiation, which can cause cataracts and other eye conditions
  • Melanin helps to protect against skin cancer and other conditions related to UV radiation exposure. It absorbs and scatters UV radiation, reducing the risk of DNA damage and skin cancer
  • Melanin contributes to the overall appearance of the skin, hair, and eyes. It determines the specific shades of color in an individual, which can enhance their natural beauty

What are the side effects of melanin supplements?

Melanin supplements are products that claim to increase the production of melanin in the body. However, there is limited scientific evidence to support the effectiveness of these supplements and their long-term safety is not well understood.

There have been some reported side effects of melanin supplements, including allergic reactions, digestive issues, and skin irritation. In some cases, these supplements have been found to contain contaminants or other substances that may be harmful to the body.

It is important to speak with a healthcare provider before taking any new supplement, including melanin supplements. They can provide guidance on the potential risks and benefits of the supplement and help to determine if it is safe and appropriate for an individual.

In general, it is best to get nutrients, including melanin, from a balanced and varied diet, rather than relying on supplements. Sun exposure is also an important source of vitamin D, which is produced when the skin is exposed to UV radiation and stimulates the production of melanin and vitamin D. However, it is important to use sun protection, such as sunscreen, to prevent overexposure to the sun.

Summary

Melanin is a pigment that is produced in the skin, hair, and eyes of humans and animals. It plays a crucial role in protecting the body from the harmful effects of the sun's ultraviolet rays. There are two types of melanin, eumelanin and pheomelanin, which are responsible for different skin and hair colors.

Melanin also has several other functions, including protecting the skin from oxidative damage, regulating body temperature, and providing immunity against certain diseases. It has been linked to several health benefits, including reducing the risk of skin cancer, protecting against age-related macular degeneration, and improving brain function.

However, there are also some potential side effects of melanin, such as skin darkening, hyperpigmentation, and melanoma, which is a type of skin cancer. While these side effects are relatively rare, it is important to be aware of them and take steps to minimize the risk.

Overall, melanin is a vital pigment with several important functions and benefits. By understanding its functions, types, and potential side effects, we can better appreciate its role in maintaining our overall health and wellbeing.

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Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
Reviewed By
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Reviewed ByDr. Bhupindera Jaswant SinghMD - Consultant PhysicianGeneral Physician

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