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Nerves (Human Anatomy): Image, Functions, Diseases and Treatments

Last Updated: Feb 02, 2023

Nerves Image

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Nerves are specialized cells in the body that transmit electrical signals between the brain and the various parts of the body. They are an important part of the nervous system, which is the part of the body that coordinates and controls how the body reacts to things going on inside and outside of it.

Nerves, which look like cables, carry electrical impulses from the brain to other parts of the body. These impulses enable sensory perception as well as muscle movement. They also aid in autonomic functions such as respiration, perspiration, and digestion.

Nerve cells, also known as neurons, are the most common name for nerve cells. Neurons can be found all over the body, but the brain and spinal cord have the most of them. Nerves, the brain, and the spinal cord comprise your nervous system.

What are the types of nerves?

There are two varieties of nerves in the human body:

  • Sensory nerves: Touch, taste, smell, and sight are facilitated by the sensory nerves' transmission of information to the brain.
  • Motor nerves: They transmit data to muscles or glands, enabling movement and function.
  • There are two main groups of nerves that come from your brain and spinal cord:
  • The 12 nerve pairs that make up the cranial nerves link the brain to the rest of the body through the head and face bones. Cranial nerves may be used for feeling, for moving, or for both. The cranial nerves control how your face moves, how your eyes move, and how you smell.
  • When leaving the spinal column, spinal nerves pair up 31 times. The sensory and motor abilities you rely on may be offered by the same set of nerves. The spinal nerves may carry sensations from your muscles and joints to your brain. The spinal nerves also regulate several reflexes and automatic responses, like withdrawing a hand from a hot stove.

Where are your nerves located?

Although many nerves originate in the brain, the spinal cord is also a significant nerve genesis location. In the arms, they protect the ulnar, median, radial, and axillary nerves. The vagus and phrenic nerves are found in the chest and abdomen. In the face are the trigeminal, optic, and facial nerves. The sural nerve, obturator nerve, femoral nerve, and sciatic nerve are the four nerves in the legs. The pudendal nerve is located in the pelvis.

What is the structure of the nerves?

Your nerves are composed of axons, which are groups of fibres that look like cords and are in the middle of the nerve. Dendrites are specialised branches which carry signals from one cell to another. In the nervous system, the endoneurium is a connective tissue layer that wraps around the axons. Fascicles, The perineurium is a layer of connective tissue that surrounds groupings of axons. Oligodendrocytes are cells found in the brain that are responsible for covering axons.

Axons exit the central nervous system and are wrapped in Schwann cells, which are encircled by other Schwann cells. Myelin can be found in oligodendrocytes and Schwann cells, and is a fatty tissue. Axons are encased in a myelin sheath, which is a multilayer structure (coating). Myelin sheath functions like the insulation around an electrical line. The speed at which nerves transmit electrical impulses is slowed by damage. Sometimes they completely stop sending out electrical impulses.

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Nerves Functions

The spinal nerves that emerge from your spinal cord are organised into 31 different pairs. These nerves have the potential to provide either sensory or motor functions, or even both. It's possible that the sensations in your muscles and joints are carried to your brain by the nerves in your spinal column. The spinal nerves are also responsible for a number of your reflexes and other automatic responses, such as when you remove your hand from a hot stove.

How do nerves function with the rest of the nervous system?

Nerves connect the two nervous system branches. The spinal cord and CNS handles external signals.These inputs affect how you move, feel, think, and act. Some responses are reflexes, which are actions that occur automatically and without any conscious thought on your part.

The axon, or 'wire' connections of the nerve, is thought of as the path an electrical impulse takes as it leaves a cell. The data is transformed into a chemical messenger at the nerve's termination point, the axon hillock. This molecule causes the secretion of neurotransmitters, which transfer messages between neurons, into the space it leaves behind. The term 'synapse' refers to these linkages.

When the neurotransmitter attaches to a receptor on the muscle or linked neuron, a second electrical signal is produced. As one neuron dies, another starts receiving and transmitting electrical signals. When the message is not delivered to the intended recipient, the method is repeated several times.

Nerves Conditions and Disorders

  • Peripheral neuropathy: The nerves on the outside of your body become injured (nerves outside the brain and spinal cord).
  • Sciatica: A painful condition that affects the sciatic nerve, which runs from the lower back down both legs, or even the nerve roots mostly in lower back.
  • Meningitis: A viral infection that manifests itself in neurological symptoms.
  • Multiple sclerosis: A neurological disorder that can induce numbness, tingling, blindness, and paralysis.
  • Encephalitis: brain infection brought on by a virus.
  • Stroke: a specific kind of stroke brought on by an obstruction in the blood supply to the brain.
  • Polio: A condition brought on by the poliovirus that harms the nerve system. Your nerves can be impacted by a wide range of illnesses, most of which lack any distinguishable symptoms. It's crucial to visit a doctor for an assessment if you encounter symptoms that could be caused by a nerve problem.
  • Epidural abscess: A pus-filled area on or inside the spinal cord.
  • Radiculopathy: A nerve root that is inflamed or swollen, which can hurt and make movement difficult.
  • Neuropathy: A nerve condition that causes pain, tingling, and numbness.
  • Parkinson's disease: An incurable disease caused by dopamine deficiency in the brain.
  • Huntington's disease: A neurodegenerative condition that mostly impacts the striatum, a region of the brain that controls movement.
  • Brain or spinal cord injury: A violent incident that causes brain or spinal cord injury.
  • Motor neuron disease: A neurodegenerative illness that impacts the motor neurons that govern muscular movement.
  • Bell's palsy: A viral infection-related illness that impacts the facial nerve, which transfers facial emotions.
  • Cranial nerve III (the oculomotor nerve): A cranial nerve responsible for eye movement.
  • Cervical spondylosis: Cervical spondylosis is a disease of the cervical spine that can result in neck discomfort and stiffness.
  • Post-concussion syndrome: Post-concussion syndrome is a disorder that can occur after a brain injury and is characterised by headaches, dizziness, and mood or sleep abnormalities.
  • Carpal tunnel syndrome: Peripheral neuropathy, a disorder induced by a sprain or lock of the wrist bones in the carpal tunnel.
  • Guillain-BarrĂ© syndrome: Guillain-BarrĂ© syndrome is a rare illness caused by a virus that harm the nerves in the body's extremities. This virus causes paralysis.
  • Epilepsy: Epilepsy is a condition that causes people to have seizures over and over again.
  • Neuralgia: A localised sensation of pain or numbness caused by dysfunction of the neurological system.
  • Migraine: Migraine is a severe headache that lasts for more than four hours.
  • Huntington chorea: Huntington's chorea is a form of movement disorder that results in motions that cannot be controlled and occur repeatedly.
  • Alzheimer disease: Brain disease induced by protein and molecule accumulation. Alzheimer's illness worsens with time. Therapies can help relieve patients.
  • Craniosynostosis: A disorder with the skull bones that causes mobility, hearing, and vision issues.
  • Brain herniation syndrome: Brain or spinal cord bulging. Accidents, childbirth, and tumours can squeeze the brain.
  • Encephalitis: A viral brain infection that may lead to major issues like seizures and coma. If untreated, encephalitis is a dangerous illness that may be fatal.
  • Astrocytoma: A specific kind of brain tumour that may be brought on by radiation and sun exposure, among other factors. Brain tumours called astrocytomas are relatively common, and they may develop fast and pose serious risks.
  • Hemangioblastoma: A kind of brain cancer called a hemangioblastoma is often brought on by a genetic mutation. Hemangioblastomas are a highly uncommon kind of brain cancer that might be challenging to identify.

Nerves Tests

  • Electromyography (EMG): An evaluation in which electrodes are used to monitor muscle activity. It is used to search for issues with how nerves interact with one another.
  • Magnetic resonance imaging (MRI): An MRI, or magnetic resonance imaging, is a medical test that uses powerful magnets and radio waves to take detailed pictures of the inside of your body. It is a completely safe and painless way for doctors to get a better look at your organs, bones, and tissues to help diagnose medical conditions
  • Fluorodeoxyglucose (FDG) PET: A test that measures the activity of tumours using a radioactive tracer.
  • Amyloid PET imaging: A diagnostic procedure that employs a radioactive tracer to detect some kinds of brain cancers. Amyloid PET imaging is a highly successful approach for diagnosing brain cancers and is often used to detect tumours in their early stages.
  • Tau PET imaging: A test that looks for tau proteins in the brain with the help of a radioactive tracer. Tau PET imaging is a good way to find out if someone has Alzheimer's disease, multiple sclerosis, or another disease that involves tau protein.
  • Single-photon emission computerised tomography (SPECT) scan: A test that uses a radioactive tracer to look for problems with how the brain sends impulses. SPECT scans are often used to find tumours as well as diseases like multiple sclerosis and Alzheimer's.
  • Dopamine transporter (DAT) scan: Dopamine transporter dysfunction may be detected using this radioactive tracer test. Diagnoses of Parkinson's disease, attention deficit hyperactivity disorder, and schizophrenia are often made using dopamine transporter scans.
  • High-density EEG: High-density electroencephalography (EEG) is a diagnostic procedure that measures brain activity electrically. Conditions including autism and ADHD, as well as TBI, are often diagnosed using high-density electroencephalograms.
  • Neuropsychological tests: Measures of intelligence and personality may be found in the results of neuropsychological testing. Diagnosing illnesses including ADD/ADHD, autism, and traumatic brain injury (TBI) requires the use of neuropsychological testing.

Nerves Treatments

  • Nerve Grafting: A procedure that involves moving nerves from one area of the body to another in order to link them. Nerve grafting is a very efficient method of treating a wide variety of diseases, including multiple sclerosis (MS), Parkinson's disease, and Alzheimer's disease.
  • Spinal cord stimulation: It is a kind of therapy for patients with injuries to the spine that involves the use of electrical currents in order to alleviate their symptoms. Spinal cord stimulation is an incredibly efficient treatment option for symptom improvement.
  • Chemotherapy: A drug-based cancer therapy. Chemotherapy treats several forms of cancer effectively.
  • Radiation therapy: Radiation kills cancer cells. Radiation treatment treats several forms of cancer effectively.
  • Surgical resection: A procedure that involves partial tumour removal. V arious types of cancer can be effectively treated through surgical resection.
  • En Bloc resection of mural nodule: A surgical procedure that sustains the surrounding tissue while removing a portion of the tumour. Many different types of cancer can be effectively treated with en bloc resection of mural nodule.
  • Reduction of mass effect: (By removing the maximum amount of the tumour while maintaining neurological function). A variety of treatments are available to help decrease the size of a tumour while preserving neurological function.
  • Craniospinal Irradiation: A cancer-killing treatment that uses radiation. Craniospinal irradiation is a highly effective treatment for a wide range of cancers.

Nerve Medicines

  • Analgesics for nerve pain: There are a diverse range of pain-relieving drugs available. Effective medications include acetaminophen, ibuprofen, and morphine.
  • Muscle relaxants for stiffness in Nerves: There are many medicines that can help make you less stiff. Meprobamate, diazepam, and carisoprodol are all useful medicines.
  • Antibiotics for an infection in the nerves: There are many antibiotics that really can effectively treat an infection. Penicillin, amoxicillin, and ciprofloxacin are all useful medicines.
  • Nutritional supplements that help relieve nerve pain: There are many supplements that can help alleviate pain. Omega-3 fatty acids, magnesium, and vitamin D are some of them. There are many different supplements that can aid your growth. Iron, folic acid, and zinc are all good examples.
  • Antivirals for treating infection of Nerves: Infections can be treated with many different antivirals. Examples include the antiviral drugs acyclovir, zidovudine, and lamivudine.
  • Chemotherapeutic medicines for Nerves: Numerous chemotherapeutic medications exist for the treatment of nerve disorders. Paclitaxel, docetaxel, and carboplatin are three that have proven effective.

How can I keep my nerves healthy?

  • Exercise regularly: Exercise helps to stimulate the production of nerve cells and can improve the function of the nervous system.
  • Get enough sleep: Sleep is important for the proper functioning of the nervous system, so be sure to get enough sleep each night.
  • Manage stress: Chronic stress can have negative effects on the nervous system, so it's important to find ways to manage stress, such as through relaxation techniques or counseling.
  • Avoid tobacco and excess alcohol: These substances can have harmful effects on the nerves.
  • Protect your nerves: Avoid activities that could potentially damage your nerves, such as excessive gripping or repetitive motions.
  • Get regular medical check-ups: Regular medical check-ups can help to identify any potential problems with your nerves and allow for early treatmen

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Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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Reviewed ByDr. Bhupindera Jaswant SinghMD - Consultant PhysicianGeneral Physician

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