One of my relative, 40 yrs female who is diagonized with schizophrenia has been using Respodal 2mg & Pacetane 2mg both grinded together and taken daily for last 6 years. Does this medicine have any effect on Menstrual cycle, after taking this she is having irregular periods, for this she did consult Dr. and used some medicine and she did have menstrual cycle once in a while not regular but finally was told may due to her age (40 yrs) she ie nearing to menopause. But recently she had gone out of station and she was not on medicine (i. E Respodal & Pacetane) she had a menstrual cycle after almost 7 months and having not taken medicine for 10 days she again started taking medicine after 10 days gap now she is having tingling on hands and she wakes up all of a sudden in night and need to message the arms. What can be the reason behind this? Earlier she also had problem like tongue has been pulled inside or twisted. Does the taking of this medicine effect Heart too.