It's been 2 years now I am getting treatment for major depression. Few months ago I was admitted also. Things are getting worse everyday. My psychiatrist had prescribed me for rtms but I didn't like their procedure. Had taken 7 sessions only. Lost interest in all the activities I used to do. I've isolated myself now. Don't feel like talking to anybody. Self destruction state. Not even getting out of bed. How can I help or motivate myself when there is no firing of dopamine in brain, I believe. Seems impossible. Not able to embrace" you gotta push yourself" therapy. Medicines I was taking a week ago: daxid100, d-venizep 200, zolcalm 10, mirtaz 30, qutan 100, lezapin 5.