I've been having acne for a long time, I have big tight cysts also on the back tha keep coming back again and again. I've tried many medication but antibiotics doesn't work on it. A dermatologist prescribed me isomond (isotretinoin. Took for about a month but i've been having some white patches because of that on face. So currently stopped it. Also I told dermatologist about the white patches, he asked to continue the medicine, also given me a cream glyco12. Currently I stopped it because I think white patches might be permanent or develop into vitiligo. Now that i've stopped white patches seems to be going slowly though. Also i've tried ayurvedic medicines. Manikya ras and gandhaka rasayana and other neem. But results were temporary.