I am taking spironolactone and bisoprolol for high blood pressure since december 2019. I am also on apixiban for a dvt in my right leg. I am a 74 years female. Since being on these meds I have put on a lot of weight, suffered with hair loss and severe knee pain (not arthritis). I also have problems with sleeping. Are there any alternative meds that might help with the side effects I am experiencing. Gp does not seem concerned.

Dr. Sameer VankarCardiologist13yrs exp

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Spiranolactone/ bisoprolol / apixaban all medicines seems to be started for valid indications. Spiranolactone may cause alopecia (hair loss) and also insomnia (sleep disturbance) bisoprolol and apixaban are very very less likely to result in the said adverse effect. Would like to know from you when was your dvt diagnosed and how long have you took apixaban and at what dose, was any scan done after 3 or 6 month interval to find residual dvt if any, and what was the cause for your dvt to decide duration of apixaban. Also would advice you few tests: 1) monitor daily bp morning and evening for 7 days 2) ecg and 2 d echo 3) lft, rft 4) fbs/ ppbs/ thyroid profile/ lipid profile based on the said investigation, would like to modify your treatment for hypertension and dvt you can consult me online after 7 days so I could help you with your problem.  

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