Resistant depression since last 10 year. Sever anxiety, antidepressant are not working. Many antidepressants and antipsychotic have tried. Ect 5 sitting taken but no response. No focus, no concentration, memory problem also. Restlessness every time, ecssesive worry about illness and future. suicidal thought coming. Please tell me about ketamine infusion therapy can response. Or thyroxine add on with antidepressant. I am 35 year old male. I have no hope that I will come back in my life. I have make a believe that I can not recover. So can I take ketamine therapy. It is a question of my life.
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Dear lybrate-user, treatment resistant depression has many add ons that are helpful in lifting your depression. First add on, will be thyroxine. It is a natural hormone and very effective along with antidepressants. Its dose can be monitored by blood test. So postpone ketamine. Be hopeful that ketamine is also available for you. Ketamine need not be infused. It can be taken as oral tablet or nasal spray.
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Hello yes, ketamine infusion helps but its effect is short lived. Most studies show that its effect will wear off in a couple of weeks, if not earlier. You will need ultimately a better course of medicines. I do not know what else have you tried for this, but normally for trd (treatment resistant depression) you will need to use a combination of a snri+ tca / snri + nassa or / snri + ssri and augment it with lithium+ low dose atypical antipsychotic. Apart from this, you can also consider vns (vagal nerve stimulation ), if this doesn't respond this augmentation strategy also.
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Stop caring too much. Always smile back or laugh at people trying to depress you with their words or other activities. It will help you to avoid them and enhance your confidence. Do not forget to make eye contact :p. Listen to your favourite music and spend your free time with your parents, because at the end only your parents will support you in your good / bad times. Try to hangout or have walk with your pet if you have one :). You will learn what unconditional love is! you will forget everything for a moment and your vision towards life will change. Keep yourself busy as much as you can. You will not get time to think of unnecessary things which lead you to depression. Most lmportant, wake up early in the morning and go to morning walk or join people doing meditation. Trust me you will be feeling very happy and healthy after that. Read books, novels etc whenever you are free. If you cannot sleep at night due to stress then wake up and start reading .you will feel better and dizzy after sometime. Try to intract with strangers alteast once per day. You will feel very confident and will not get depressive thoughts. Go to your appstore and download this amazing app yourdost. Main advantage of this app is you can share your problems chasing you and you can get solutions from professionals. Its a very good app. Play outdoor games specially with childern :). Have a adventurous trip with your friends or family. Watch tv series you like.
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