My mother (Age 51, weight 69 kg) has osteoarthritis and the synovial fluid of the right knee (Arthritis grade 4) is nearly gone but the bones of the left leg started to bend and paining more severe from 2 month on wards. And BMD results shows osteoporosis (T-Score = -4.06) (Z Score = -2.63) but uric acid and serum calcium is normal. She also has mild diabetes and High BP (140/80). Should we go for the knee replacement surgery or is there any alternative of this surgery? And Can knee replacement surgery successful in osteoporosis bones?