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Focal active colitis (FAC) is a histologic pattern of injury, not a specific diagnosis. From a morphologic standpoint, FAC is defined either as a single focus of neutrophilic crypt injury (cryptitis) or as multiple separate foci of cryptitis occurring in different pieces of tissue within the same biopsy specimen.The most common include: Inflammatory bowel disease (IBD) colitis (Crohn's disease or ulcerative colitis) ... Ischemic colitis. Infectious colitis (food poisoning caused by infections, and infections caused by parasites or bacteria)
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