HI, Last time my son's blood test report gave a note: RBCs: Mild anisopoikilocytosis. Predominantly microcytic hypochromic cells with ovalocytes, elliptocytes are seen. Advised: HbA2/HbF estimation What does this mean?

Dr. Sajeev KumarGeneral Physician33yrs exp

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The given report shows your son had mild anemia and blood cells are of different shapes and you have been asked to do these tests to see normalcy of his condition .The term Hereditary Persistence of Foetal Haemoglobin (HPFH) is used to define a group of conditions characterised by increased levels of HbF in adults, due to a persistent synthesis of ?-globin chains after birth without any significant clinical or haematological manifestations. HbA2, composing of two ? chains and two chains, is a minor component of the hemoglobin present in normal adult red blood cells, accounting for about 2.5% of the total hemoglobin in healthy individuals.  

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