My wife, 65 years old, is under treatment for thyroid disorder with thyronorm 100 mcg from january 2010. On january 2016 tests indicated tsh -0.01uiu/ml and t4-5 ug/dl & thyronorm 75 mcg was advised. On december 2017 test results were t4-9.5 & tsh-1.21.she started thyronorm 100 mcg and at present on 8/02/19 test results were t3-89 ng/dl, t4-12. 51ug/dl & tsh - 0.08 uiu/ml. Now please advise me whether going back to thyronorm 75 mcg will reduce t4 level to normal or she has to start thyronorm 125 mcg.

Dr. Prabhakar Laxman JatharEndocrinologist48yrs exp

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Hello, Thanks for the query. I have seen the details, it is a bit surprising to know when TSH was 1.21 mU/L, dose was increased to 100 mcg of Thyroxine. Ideally when adequate dosage is taken (of Levothyroxine) TSh should be maintained aroun 3 to 4 mU/L. Now as the TSh is down to 0.08 mU/L, dosage of Levothyroxine needs to be reduced to either 75 mcg or even 62.5 mcg per day. Then check TSH after 6 weeks to see what has been the benefit. Very low TSH can give symptoms of Hyperthyroidism. If you have any questions please do come back. Thanks. 

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