Hi, Please suggest what happens if we take 30 tablet thyronorm 75 mcg tablets at same time? Does it may lead to death or not?

Dr. Sajeev KumarGeneral Physician34yrs exp

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Ingested thyroxine, which is itself probably of modest physiologic significance, is rapidly partially converted to triiodothyronine (t3), the active form of thyroid hormone. Both thyroxine and triiodothyronine levels in serum rise within 1-2 hours of ingestion. Agents that inhibit t4>t3 conversion provide one approach to treatment. In children and adolescents, the clinical course is often very mild. Patients in this age range may ingest a full flask of lt4 with 90-100 tablets (100 or 150 mcg/tablet). Rarely, the overdose is discovered immediately and the patient is brought to the hospital 6-12 hours after the ingestion. At this time, the common clinical signs and symptoms include nervousness, insomnia, mild tremor of hands, tachycardia, mild elevation of body temperature, blood pressure elevation, and loose stools. Rarely more serious late effects occur, including coma, convulsions, and acute psychosis. Cardiac effects aside from tachycardia are seldom seen in young adults but may occur in middle age and older adults, with reported arrhythmias and acute myocardial infarction. However, only one fatality has been reported. Interestingly the onset of symptoms and signs.  

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