Hi sir, my husband is taking alcohol after 4 years and I am giving him disulfiram 250 mg without knowing him. When he consume alcohol his eyes becomes reddish and face will be bulged and suffocation finally he will vomit sir. Because of these is he have any chance to get any side effects or any problem sir I need some suggestion to withdraw from alcohol permentaly sir.

Dr. Prabhakar Laxman JatharEndocrinologist48yrs exp

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Hello, thanks for the query. Usually disulfuram is given as adjunct to psychotherapy. That is once patient agrees to stay away from alcohol after proper counselling. The drugs is started after a person abstains from alcohol for about 2 weeks. Initially 250 mg once or twice a day. Then maintained on the same dose for many days, weeks or even months. If person takes alcohol while on this drugs then there is a reaction to to alcohol leading to vomiting it out. Best way to make the treatment effective is get the person's involvement and commitment to stop alcohol consumption. So if possible please consider meeting a psychoanalyst or psychiatrist with the concurrence of your husband. That is the best option. The drug can be taken for a long time. Thanks.  

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