My father is having problems with bones pain in wrist and knee from sometime now. It was started with wrist pain and when we consulted doctor they told it's due to tb arthritis in wrist and started att medication since may. From last one month his pain in knee and leg below knee has increased very much and it starts daily from evening onwards and gets worse during night till morning. Because of this he couldn't sleep and someday pain seems like unbearable. When the pain is more he is not able to stand straight and he complains his bones seems to get tighter. Sometime he sweats a lot while sleeping or during in any activity. Attaching the history of injury and current medications. Kindly suggest what could the reason of increase pain in night on daily basis and how can we get some relief. Is there some issues with medication prescription? Does att making things worse or any other medications? What other options we can opt to help him without knee replacement surgery?