Dear Dr. Between glycomet gp1 and teng?yn m 500 which is the stronger dosage and which one I suggest for patient with 130 fasting sugar anr 220 after food.

Question

Hello, Thanks for the query.
I have seen the details mentioned. The drugs mentioned Glimiperide and Tenelegliptin both are totally different compounds having totally different modes of action like glimiperide is a sulfanylurea with action directly on Beta cell  that causes release of insulin independent of food present in the gut. Tenelegliptin is a DPP-IV inhibitor has action through incretin based system which releases insulin based on presence of glucose in the gut. Both are quite good. A diabetologist will decide the need based on patient's glucose levels, dietary pattern and need. 
Another aspect which is unclear to me is that why are you zuggesting the treatment to the patient? Are you a treating doctor? Please clarify. Thanks.

Prabhakar Laxman Jathar · Accepted Answer

Hello, Thanks for the query.
I have seen the details mentioned. The drugs mentioned Glimiperide and Tenelegliptin both are totally different compounds having totally different modes of action like glimiperide is a sulfanylurea with action directly on Beta cell  that causes release of insulin independent of food present in the gut. Tenelegliptin is a DPP-IV inhibitor has action through incretin based system which releases insulin based on presence of glucose in the gut. Both are quite good. A diabetologist will decide the need based on patient's glucose levels, dietary pattern and need. 
Another aspect which is unclear to me is that why are you zuggesting the treatment to the patient? Are you a treating doctor? Please clarify. Thanks.

Pramod Kumar Sharma · Answer

There no comparision, intially choose either of them.

K. Pratheba Nandhakumar · Answer

For this blood sugar levels I would suggest you to take t.tenglyn m 20/500 once daily. Recheck sugar levels after 2 wks and let me know!