My mother, 62 years of age has been suffering from dementia and depression since 2016. She was prescribed dveniz, daxid for depression and admenta (bds), aricep (ods) for dementia since september, 2016. The disease has progressed albeit slowly. But there had been behavioral changes specially repetitive behaviour, frequent fits of aggression etc. Because of the increased aggressive tendencies, her doctor asked to stop antidepressants in january 2020. aggressive behavior dwindled down after that. However it increased a bit since december 2020. Due to unavailability of the previous psychiatrist we had to consult a separate psychiatrist in february, 2021. He started a new drug, olanzapine 2.5 (ods). My mother started taking the drug since february 10th. However she started getting quite drowsy from the middle of march. So we had to visit the doctor on march 26th. He asked to stop olanzapine 2.5 and continue with aricep and admenta. She was more or less fine till last tuesday, 6th april. But suddenly from 7th april there was a total change in everything. It's almost like she's spellbound! totally lost and not being able to do basic daily activities. It's almost like her brain has been switched off. She's walking slowly, not being able to eat/ drink on her own. And since yesterday she's having trouble using the toilet too. Not being able to pass urine or stools. Is this because of the drug olanzapine? If so, then can some other drug be used to negate these side effects of olanzapine?
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It is most likely her dementia is progressing and has done so to such an extent she has developed this block. Get a repeat ct or mri brain done and compare with the one taken initially it will through more light. Most of the drugs given by your psychiatrists are aimed towards the behavioural problems associated with dementia and they have given very low dose as well. So it is unlikely those effects are carried forwards. Good luck.
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Dear lybrate-user, sorry to know about your mom's sudden setback. It is definitely not due to olanzapine. It is all in the course of dementia. I don't know about her diagnosis of dementia and medical history. If it is a vascular dementia, she might have suffered a cerebrovascular accident - like brain hemorrhage or clot. Or some metabolic changes might have caused - like sodium, water, sugar level changes. Anyway she needs admission and investigations for the cause of her set back. There are few treatable causes that can bring back her daily activities.
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Its a chronic case, so it will take to survive, you may give her two doses gels 200 once in the morning, damiana q 10 drops twice daily kali phos 3x 4tabs twice daily if needed contact me by. Phone m mobile.
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It is sad to convey but symptoms you suggested are of disease progression and not because of side effects of on going medications.
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