I am 35 years old lady. 3 years back I had depression and anxiety. I was prescribed nexito 20 mg with 0.75 mg lexotanil to take in the morning. And at night mirtazapine 15 mg. I felt better and was back to my normal life. But continued with this medicines. Recently 2 months back I started having severe depression. And was prescribed cipralex 20 mg instead of nexito. But it did not work out. Now have been prescribed fluoxetine 20 mg with 0.75 mg lexotanil in the morning. And at 8 pm mirtazapine 15 mg. Later bedtime amitriptyline 25 mg. But still I feel low, no mood, tired,get panic attacks and anxiety. Please assist. Thank you.

Dr. Prof. Jagadeesan M.S.Psychiatrist17yrs exp

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Your recurrence of depressive symptoms is due to the nature of the depressive episode/ persistent depressive disorder, which are the likely reaosns. In fact cipralex and nexito are the same molecule and cipralex works much better than nexito because of the purity of the molecule. Though fluoxetine, mirtazapine have been tried, there are better combinations available to get you off the depressive symptoms in a week or two. Get an opinion from an astute psychiatrist, if things do not improve. Good luck.  

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Dr. P K SukumaranPsychiatrist56yrs exp

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Dear lybrate-user your first treatment is better continue that depression is a very common problem. There are so ever so many much worse than u. Yours is a little problem no need to worry. Stop smoking and alcohol have regular exercise like walking swimming cycling jogging with friends for one hour holidays once in a week dailyyoga, scheduling activities hobbies social service take fish and vegetables take nexito 10 mg daily exercise you are having social phobia and depression. No need to worry. Exercise one hour daily yoga and breathing exercise all the best.  

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Dr. Saranya DevanathanPsychiatrist50yrs exp

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Dear lybrate-user, both nexito and cipralex are escitalopram from different phamacautical companies. Some combination of antidepressants like fluoxetine, mirtazapine and amitriptyline may work for you. At times depression gets treated fast, especially when you are younger and you started the tablet late when the depression is about go away by itself. Since you are getting recurrent episodes of depression, your diagnosis may be changed to bipolar depression and a mood stabiliser may be added for better improvement. Please discuss with your psychiatrist.  

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