My mother has developed gall bladder carcinoma it was first diagnosed on 21 march 21, after that her usg guided fnac, gall bladder fossa mass was done in rajiv gandhi cancer institute and research center which shows positive for malignancy - poorly differentiated carcinoma. Her chemo (carboplatin and gemcitabine) was done on 20th april after which she developed cavity infection and further chemo were delayed for more than a month ,her next chemo were scheduled on 4, 11 and 28th june, after 2nd chemo of june she developed pain due to ascites in gb fossa region and perihaptic region which was aspirated on 28th. Ct scan of 26 & 27 show lesion is infiltrating liver parenchyma along segment 4b 5 and 6. Medially lesion is infiltrating antro pyloric region of stomach & lateral wall of 1st and 2nd part of duodenum ,resultant wall thickening ,inferiorly the exophytic component is infiltrating hepatic flexure of colon with frank fistulous communication between mass and colon. Ct of 27th shows progressive disease. She is given 1 chemo of oxaliplatin on 28th july & next chemo will be on 4th. How shall she be treated?

Dr. Santosh Kumar ChoudkiGeneral Surgeon2yrs exp

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Hello lybrate-user we are very regret to know your mother conditions. Anyway i'll suggest you regarding this good palliative care is the only necessary as of now with supportive measures. Look according to criteria says malignancies are more prone to leading cause of death now a days with advanced agers like your mother. Just according my opinion you have to continue some anti cancer medications which i'll stop the progressions as mets as of now and give some nutritional support by home remidies only not a medications and little doses of painkillers when the pain is severe otherwise nuthing. Tysm for posting your queries here keep posting to get suggestions from expertise doctors and I wish to god to give strength and as much she can live with a her abilities.  

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Dr. Adnan MattooGeneral Surgeon2021yrs exp

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Hello ca gallbladder is a very bad ca ant one can have. Giving chemo and all may give few months more and decrease the sufferings n pain. But the prognosis is bad . Most of the treatment is directed towards alleviating pain , ascites, jaundice etc. complete cure is rare. May God ease her sufferings Regards  

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Dr. Girish PratapGeneral Surgeon32yrs exp

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You need to be strong as the prognosis is not very encouraging considering the asities and local infilteration. Chemotherapy is only option which is possible only if the patient is fit enough to bear it which is less likely in your mothers case. Sorry to give you a unfavorable answer but every caretaker for cancer patients should be informed the facts. Monitor blood sugar regularly or she may go into hypoglycemia (low blood sugar) with glyciphage 1000 if her oral intake is poor.  

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