I took microcytic hypochromic anaemia treatment for 2 months (hb was 7.8) and got sudden acne flare up all over my face and neck and also gained 6 kg weight. I read that that taking vitamin b12 increases the amount of that vitamin on facial skin. This, in turn, causes a certain facial bacteria (propionibacterium acnes) to produce more of something called piriformis, which results in inflammation. And this could lead to acne. Before treatment my vitamin b12 levels were 362 pg/ml (211-911), folate was 9.20, ferritin - 56, plasma glucose random - hexokinase 106 and I was given 1500 mg methylcobalamin, folic acid 5 mg, ferrous sulphate 200 mg bd, ascorbic acid 500 mg bd for 2 months everyday. My lymphocytes are 51. It has been 10 days after stopping this medication but still new pus filled acne is coming everyday. Could it be because of methylcobalamin or high lymphocytes? Should I get porphyrins tests done? What to do for acne caused due to vitamin b12?