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You a 50 year old patient Mr. X who is a diabetic for past 15 years and was on t. Metformin 500 mg +t.glimepiride 1 mg sr od came with reports for review. The report showed fbs -230 mg/dl and ppbs - 300 mg/dl, blood urea -44 and s.creatinine 2.2 .patient complaints of edema and frothy urine. Now patient was started on t. Metformin 1gm + t. Glimepiride 1 mg sr od and t. dapagliflozin 5 mg and asked to review after month? After one month patient reports was surprisingly fbs -230 mg/dl, ppbs - 420 mg/dl, hba1c -12, b.urea - 46, s. Creatinine - 2.3.what could have resulted in high sugar values.
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Hello, thanks for the query. I have seen the details given. From the information given it appears that oral drugs are unable to control the glucose levels as required. Another aspect there is no mention of patient's weight, height, dietary pattern, extent of physical activity, bp readings and lipid profile. As all these matter in proper control of the glucose levels. Further with a hba1c% of 12%, it is essential to add insulin to the therapy. It is better to start with a basal insulin along with present treatment. Thanks.
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