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I am 60 years old has diabetes type b for last 15 years. At the moment I have to take humalog mix 50 total 60 units to keep sugar level under control. My hba1c is 6.5. My doctor says my dose is high because insulin resistance. My body creates anti bodies to destroy the insulin. It should reduce with passage of time, however, if I reduce the dose my blood glucose level shoots up. I am following very strict diet and exercise regime. However, the insulin dose is not reducing. Can you suggest me any alternative?
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In t2dm there are no antibodies produced against insulin, it is the insulin resistance that is the culprit along with improper production of insulin by beta cells of pancreas. You might a drug like metformin 500 mg twice a day in addition to insulin which would reduce insulin resistance and help insulin action. Plus your strict diet and exercising for more than 1 h a day should continue.
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