I am a patient of ankylosing spondylitis. Hlab 27 positive. Age 34 years male. My crp 70, esr 70, hemoglobin 10.2 I am taking (veloz 20 mg, nucoxia 90 mg, saaz d's )1tablet per day. Still my crp is increasing. Dr. Suggest me to take biologic injection. But it is so costly an I scared that if I take this once can not stop. Oral medicine will not respond perfectly after biologic. What I do? please suggest me I am very nervus.