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Q) to ONCOLOGIST-- 74 years old male with a case of Adenocarcinoma of oesophagus and we have given three chemotherapy cycle and his Upper GISCOPY shows decrease in the lesion and even PET scan shows complete resolution of all the nodes. But the values of tumor markers -- 1) NSE - previous - 20.14 and after chemo - 28.5 2) beta2 microglobulin - previous -2713 and after chemo - 2753 I want to know the reason for increase in the values of tumour marker after chemotherapy.
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Dear lybrate-user, adenocarcinoma in esophagus occurs at the lower end. Unless contraindicated treatment is by surgery. Rising markers after chemotherapy suggests the spread elsewhere though locally there is good response.
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